Chapter 29: Q51. (page 1194)
Draw the structure for each peptide:
(a) Phe–Ala;
(b) Gly–Gln;
(c) Lys–Gly;
(d) R-H
Short Answer
c.
d.
Chapter 29: Q51. (page 1194)
Draw the structure for each peptide:
(a) Phe–Ala;
(b) Gly–Gln;
(c) Lys–Gly;
(d) R-H
c.
d.
All the tools & learning materials you need for study success - in one app.
Get started for freeDraw the organic products formed in the following reaction.
Consider two molecules of a tetrapeptide composed of only alanine residues. Draw the hydrogen bonding interactions that result when these two peptides adopt a parallel β-pleated sheet arrangement. Answer this same question for the antiparallel β-pleated sheet arrangement.
Another method to form a peptide bond involves a two-step process:
[1] Conversion of a Boc-protected amino acid to a p-nitrophenyl ester.
[2] Reaction of the p-nitrophenyl ester with an amino acid ester.
Why does a p-nitrophenyl ester “activate” the carboxy group of the first amino acid to amide formation?
Would a p-methoxyphenyl ester perform the same function? Why or why not?
Identify A–E in the following reaction sequence.
Besides the Boc and Fmoc protecting groups used in peptide synthesis, amines can also be protected by reaction with benzyl chloroformate (). Draw the structure of the product formed by reaction of alanine with benzyl chloroformate
What do you think about this solution?
We value your feedback to improve our textbook solutions.