Chapter 29: Q60. (page 1196)
Draw the organic products formed in each reaction.
Chapter 29: Q60. (page 1196)
Draw the organic products formed in each reaction.
All the tools & learning materials you need for study success - in one app.
Get started for freeQuestion:Gramicidin S, a topical antibiotic produced by the bacterium Bacillus brevis, is a cyclic decapeptide formed from five amino acids. Draw the structures of the amino acids that form gramicidin S, and explain why this compound possesses two unusual structural features.
Which of the following amino acids are typically found in the interior of a globular protein, and which are typically found on the surface: (a)phenylalanine; (b)aspartic acid; (c) lysine; (d) isoleucine; (e) arginine; (f) glutamic acid?
Another method to form a peptide bond involves a two-step process:
[1] Conversion of a Boc-protected amino acid to a p-nitrophenyl ester.
[2] Reaction of the p-nitrophenyl ester with an amino acid ester.
Why does a p-nitrophenyl ester “activate” the carboxy group of the first amino acid to amide formation?
Would a p-methoxyphenyl ester perform the same function? Why or why not?
Devise a stepwise synthesis of the tripeptide Val-leu-Val from 3-methylbutanal as the only organic starting material. You may also use any required inorganic or organic reagents.
What is the predominant form of each of the following amino acids at pH=11? What is the overall charge on the amino acid? (a)valine; (b)proline; (c)glutamic acid; (d)lysine?
What do you think about this solution?
We value your feedback to improve our textbook solutions.