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Chapter 17: Q.5. (page 641)

Question: What is the structure of propofol, which has the IUPAC name 2,6-diisopropylphenol? Propofol is an intravenous medication used to induce and maintain anesthesia.

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Structure of propofol

Step by step solution

01

Propofol

Propofol, also known as ‘Milk of amnesia’ is an alkyl derivate of phenol synthesized by Friedel Craft’s alkylation of phenol.

02

Structures of Propofol

IUPAC name: 2,6-diisopropylphenol

Phenol - benzene ring with -OH group

diisopropyl - two isopropyl group

2,6 - position of isopropyl groups with respect to -OH group of phenol

Structure of Propofol

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Most popular questions from this chapter

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Question: Hydrocarbon A possesses a significant dipole, even though it is composed of only C-C and C-H bonds. Explain why the dipole arises and use resonance structures to illustrate the direction of the dipole. Which ring is more electron rich?

Question: Use the inscribed polygon method to show the pattern of molecular orbitals in cyclooctatetraene.

a. Label the MOs as bonding, antibonding, or nonbonding.

b. Indicate the arrangement of electrons in these orbitals for cyclooctatetraene, and explain why cyclooctatetraene is not aromatic.

c. Treatment of cyclooctatetraene with potassium forms a dianion. How manyπelectrons does this dianion contain?

d. How are the πelectrons in this dianion arranged in the molecular orbitals?

e. Classify the dianion of cyclooctatetraene as aromatic, antiaromatic, or not aromatic, and explain why this is so.

Question: Draw all aromatic hydrocarbons that have molecular formula C8H10. For each compound, determine how many isomers of molecular formula C8H9Brwould be formed if one H atom on the benzene ring were replaced by a Br atom.

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