Chapter 26: Q 8. (page 1049)
What starting materials are needed to prepare each compound using a Heck reaction?
Short Answer
Answer
a.
b.
c.
Chapter 26: Q 8. (page 1049)
What starting materials are needed to prepare each compound using a Heck reaction?
Answer
a.
b.
c.
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Get started for freeDraw the product formed from ring-closing metathesis of each compound.
a.
b.
Devise a synthesis of the given trans vinylborane, which can be used for bombykol synthesis (Figure 26.1). All of the carbon atoms in the vinylborane must come from acetylene, nonane-1,9-diol, and catecholborane.
Identify X, an intermediate that was converted to eletriptan (trade name Relpax), a drug used to treat migraines.
What product is formed when each alkene is treated with and Zn(Cu)?
a.
b.
c.
Bi-aryls, compounds containing two aromatic rings joined by a C-C bond, can often be efficiently made by two different Suzuki couplings; that is, either aromatic ring can be used to form the organoborane needed for coupling. In some cases, however, only one route is possible. With this in mind, synthesize each of the following bi-aryls using benzene as the starting material for each aromatic ring. When more than one route is possible, draw both of them. You may use any required organic or inorganic reagents.
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