Chapter 24: Q.23. (page 962)
Question: What product is formed when each pair of compounds is treated with NaOEt in ethanol?
Short Answer
Answer
Chapter 24: Q.23. (page 962)
Question: What product is formed when each pair of compounds is treated with NaOEt in ethanol?
Answer
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Question: What product is formed when a solution of A and B is treated with mild base? This reaction is the first step in the synthesis of rosuvastatin (sold as a calcium salt under the trade name Crestor), a drug used to treat patients with high cholesterol.
Question: 4-Methylpyridine reacts with benzaldehyde in the presence of a base to form A.
(a) Draw a stepwise mechanism for this reaction.
(b) Would you expect 2-methylpyridine or 3-methylpyridine to undergo a similar type of condensation reaction? Explain why or why not.
Question: Devise a synthesis of each compound from cyclopentanone, benzene, and organic alcohols having ≤ 3 C's. You may also use any required organic or inorganic reagents.
Question: Draw a stepwise mechanism for the following variation of the aldol reaction, often called a nitro aldol reaction.
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