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Chapter 5: Q.50 (page 208)

Draw the structure of (S)-citalopram, a drug used to treat depression and anxiety that is much more potent than its R enantiomer.

citalopram

Short Answer

Expert verified

The structure of the (S)-citalopram is as follows:

Step by step solution

01

The R and S isomers

The enantiomers are named R and S according to the spatial arrangement of the different groups attached to them.

The two enantiomers of a compound have the same physical properties.

02

The strucuture of (S)-citalopram

Citalopram is a drug used to treat depression and anxiety. The (S)-citalopram is more potent than its R isomer. Following is the structure of (S)-citalopram:

S isomer

The R isomer of citalopram has the following structure:

R isomer

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Most popular questions from this chapter

a. Locate the stereogenic centres in the ball-and-stick model of lisinopril, a drug used to treat high blood pressure.

b. Label each stereogenic centre as R or S.

Locate the stereogenic centers in each molecule. Compounds may have one or more stereogenic centers.

a.

b.

c.

d.

e.

f.

Label each compound as chiral or achiral.

a.

b.

c.

d.

a) Locate the stereogenic centers in the ball-and-stick model of ezetimibe (trade name Zetia), a cholesterol-lowering drug. (b) Label each stereogenic center as R or S.

(S)-Lactic acid has a specific rotation of +3.8. (a) If the ee of a solution of lactic acid is 60%, what is[α]this solution? (b) How much of a dextrorotatory and levorotatory isomer does the solution contain?
See all solutions

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