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Chapter 23: Q7. (page 924)

Question: Draw the product formed when each starting material is treated with LDA in THF solution at –780C.

Short Answer

Expert verified

Answer

The products formed when each starting material is treated with LDA are shown below.

Step by step solution

01

Definition of LDA

LDA is a non-nucleophilic strong base that abstracts protons from the least hindered C-H group.

02

Function of LDA

Due to its bulky nature due to the attached isopropyl groups with the nitrogen atom, it always acts as a base. It withdraws protons from the least hindered site.

The products of the given reaction are:

Reaction of a

Reaction of b

Reaction of c

Reaction of d

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