Chapter 18: Problem 6
Complete the following transesterification reaction (the stoichiometry is given in the equation).
Chapter 18: Problem 6
Complete the following transesterification reaction (the stoichiometry is given in the equation).
All the tools & learning materials you need for study success - in one app.
Get started for freeTreating choline with acetic anhydride gives acetylcholine, a neurotransmitter. Write an equation for the formation of acetylcholine.
Draw a structural formula for each compound. (a) NCyclohexylacetamide (b) 1-Methylpropyl methanoate (c) Cyclobutyl butanoate (d) \(N\) (1-Methylheptyl) succinimide (e) Diethyl adipate (f) 2-Aminopropanamide
Propose a synthesis for diphenhydramine starting from benzene, benzoic acid, and 2- \((N, N-\) dimethylamino) ethanol.
Barbiturates are prepared by treating a derivative of diethyl malonate with urea in the presence of sodium ethoxide as a catalyst. Following is an equation for the preparation of barbital, a long-duration hypnotic and sedative, from diethyl diethylmalonate and urea. Barbital is prescribed under one of a dozen or more trade names. (a) Propose a mechanism for this reaction. (b) The \(\mathrm{p} K_{\mathrm{a}}\) of barbital is \(7.4\). Which is the most acidic hydrogen in this molecule? How do you account for its acidity?
Following is a retrosynthetic analysis for the synthesis of the herbicide ( \(S\) )-Metolachlor from 2-ethyl-6-methylaniline, chloroacetic acid, acetone, and methanol. Show reagents and experimental conditions for the synthesis of Metolachlor from these four organic starting materials. Your syn thesis will most likely give a racemic mixture. The chiral catalyst used by Novartis for reduction in Step 2 gives \(80 \%\) enantiomeric excess of the \(S\) enantiomer.
What do you think about this solution?
We value your feedback to improve our textbook solutions.