Chapter 19: Problem 75
Using your roadmaps as a guide, show how to convert ethanol into 2-pentanone. You must use ethanol as the source of all carbon atoms in the target molecule. Show all reagents and all molecules synthesized along the way.
Chapter 19: Problem 75
Using your roadmaps as a guide, show how to convert ethanol into 2-pentanone. You must use ethanol as the source of all carbon atoms in the target molecule. Show all reagents and all molecules synthesized along the way.
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Get started for freeShow how the malonic ester synthesis can be used to prepare the following substituted acetic acids.
Show how to synthesize the following compounds using either the malonic ester synthesis or the acetoacetic ester synthesis. (a) 4-Phenyl-2-butanone (b) 2-Methylhexanoic acid (c) S-Ethyl-2-pentanone (d) 2-Propyl-1, 3 -propanediol (e) 4-Oxopentanoic acid (f) 3-Benzyl-5-hexene-2-one (g) Cyclopropanecarboxylic acid (h) Cyclobutyl methyl ketone
Write a mechanism for the hydrolysis of the following iminium chloride in aqueous HCl.
2-Propylpentanoic acid (valproic acid) is an effective drug for treatment of several types of epilepsy, particularly absence seizures, which are generalized epileptic seizures characterized by brief and abrupt loss of consciousness. Propose a synthesis of valproic acid starting with diethyl malonate.
Propose two syntheses of 4-phenyl-2-pentanone, each involving conjugate addition of a lithium diorganocopper reagent.
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