Log out Go to App
Go to App

Learning Materials

Features

Discover

Chapter 27: Problem 19

Histamine is synthesized from one of the 20 protein-derived amino acids. Suggest which amino acid is its biochemical precursor and the type of organic reaction(s) involved in its biosynthesis (for example, oxidation, reduction, decarboxylation, nucleophilic substitution).

Short Answer

Expert verified
Answer: Histidine serves as a precursor for histamine biosynthesis, and the primary type of organic reaction involved in this process is decarboxylation.

Step by step solution

01

Identify the biochemical precursor of histamine

Histamine is derived from the amino acid histidine. So, histidine is the biochemical precursor for histamine.
02

Recognize the type of reactions involved in histamine biosynthesis

In the biosynthesis of histamine from histidine, the carboxyl group (COOH) is removed from the histidine molecule, followed by the formation of a new bond between the nitrogen in the imidazole ring and a hydrogen atom. The biochemical reaction involved in transforming histidine to histamine is a decarboxylation reaction.
03

Conclude

The amino acid that serves as a precursor for histamine biosynthesis is histidine, and the primary type of organic reaction involved in this process is decarboxylation.

Unlock Step-by-Step Solutions & Ace Your Exams!

  • Full Textbook Solutions

    Get detailed explanations and key concepts

  • Unlimited Al creation

    Al flashcards, explanations, exams and more...

  • Ads-free access

    To over 500 millions flashcards

  • Money-back guarantee

    We refund you if you fail your exam.

Start your free trial

Over 30 million students worldwide already upgrade their learning with Vaia!

One App. One Place for Learning.

All the tools & learning materials you need for study success - in one app.

Get started for free

Most popular questions from this chapter

Write the zwitterion form of alanine and show its reaction with the following. (a) \(1 \mathrm{~mol} \mathrm{NaOH}\) (b) \(1 \mathrm{~mol} \mathrm{HCl}\)

What amino acid does each abbreviation stand for? (a) Phe (b) Ser (c) Asp (d) Gln (e) His (f) Gly (g) Tyr

Several \(\beta\)-amino acids exist. There is a unit of \(\beta\)-alanine, for example, contained within the structure of coenzyme A (Problem 25.35). Write the structural formula of \(\beta\)-alanine.

As discussed in Chemical Connections: "Vitamin \(\mathrm{K}\), Blood Clotting, and Basicity" in Section \(26.6 \mathrm{D}\), vitamin \(\mathrm{K}\) participates in carboxylation of glutamic acid residues of the blood-clotting protein prothrombin. (a) Write a structural formula for \(\gamma\)-carboxyglutamic acid. (b) Account for the fact that the presence of \(\gamma\)-carboxyglutamic acid escaped detection for many years; on routine amino acid analyses, only glutamic acid was detected.

From which amino acid are serotonin and melatonin synthesized, and what types of reactions are involved in their biosynthesis? a. b.
See all solutions

Recommended explanations on Chemistry Textbooks

Organic Chemistry

Read Explanation

Nuclear Chemistry

Read Explanation

Kinetics

Read Explanation

Chemistry Branches

Read Explanation

The Earths Atmosphere

Read Explanation

Chemical Reactions

Read Explanation
View all explanations

What do you think about this solution?

We value your feedback to improve our textbook solutions.

Study anywhere. Anytime. Across all devices.

Sign-up for free