Log out Go to App
Go to App

Learning Materials

Features

Discover

Chapter 24: Q20P (page 1282)

Show the third and fourth steps in the sequencing of oxytocin. Use figure 24-14 as a guide.

Short Answer

Expert verified

The most efficient method for sequencing peptides is Edman degradation. In this process, a peptide is treated with phenyl isothiocyanate that is followed by hydrolysis. The products formed from the degradation process are the peptide chain which is a shortened one and a heterocyclic derivative of the terminal amino acid known as phenylthiohydantoin.

Step by step solution

01

Edman degradation

The most efficient method for sequencing peptides is Edman degradation. In this process, a peptide is treated with phenyl isothiocyanate that is followed by hydrolysis. The products formed from the degradation process are the peptide chain which is a shortened one and a heterocyclic derivative of the terminal amino acid known as phenylthiohydantoin.

02

 First two steps in sequencing of oxytocin

The first two steps in sequencing oxytocin involves Edman degradation which cleaves the terminal amino acid and as a result of it, phenylthiohydantoin derivative is formed. The shortened peptide is readily available for the next steps.

03

 Third and fourth steps in sequencing of oxytocin

The third and fourth step in the sequencing of oxytocin are represented by the figures as shown below.

Unlock Step-by-Step Solutions & Ace Your Exams!

  • Full Textbook Solutions

    Get detailed explanations and key concepts

  • Unlimited Al creation

    Al flashcards, explanations, exams and more...

  • Ads-free access

    To over 500 millions flashcards

  • Money-back guarantee

    We refund you if you fail your exam.

Start your free trial

Over 30 million students worldwide already upgrade their learning with Vaia!

One App. One Place for Learning.

All the tools & learning materials you need for study success - in one app.

Get started for free

Most popular questions from this chapter

Draw the electrophoretic separation of Ala, Lys, and Asp at pH 9.7.

Show the steps and intermediates in the synthesis of Leu-Ala-Phe by the solid-phase process.

Question. Propose a mechanism for the coupling of acetic acid and aniline using DCC as a coupling agent.

Daw the structure of the predominant form of

Isoleucine at pH 11 (b) Proline at pH 2

Arginine at pH 7 (d) Glutamic acid at pH 7

A mixture of alanine, lysine, and aspartic acid at 1). pH 6 ; 2). pH 11; 3). pH

Draw the structure of the predominant form of

(a)Isoleucine at pH 11 (b) Proline at pH 2

(c)Arginine at pH 7 (d) Glutamic acid at pH 7

A mixture of alanine, lysine, and aspartic acid at 1). pH 6 ; 2). pH 11; 3). pH 2
See all solutions

Recommended explanations on Chemistry Textbooks

Chemical Reactions

Read Explanation

Physical Chemistry

Read Explanation

Ionic and Molecular Compounds

Read Explanation

Organic Chemistry

Read Explanation

The Earths Atmosphere

Read Explanation

Making Measurements

Read Explanation
View all explanations

What do you think about this solution?

We value your feedback to improve our textbook solutions.

Study anywhere. Anytime. Across all devices.

Sign-up for free