Explanations 
Textbooks 
Exams 
GCSE 
IGCSE 
AS 
A Level 
International A Level 
University Admissions Tests 
Flashcards 
Vaia AI 
Notes 
Study Plans 
Study Sets 
Find a job 
Find a degree 
Student Deals 
Magazine 
Mobile App Chapter 21: Q36P-c (page 1129)
Show how you would accomplish the following synthetic transformations. You may use any necessary reagents.
Short Answer
Synthetic transformation for pyrrolidine to N-acetylpyrrolidine is show as,
Step by step solution
Step-by-Step SolutionStep 1: Use of acetyl chloride
Acetic anhydride would work as well as acetyl chloride, a base such as pyridine or sodium bicarbonate or triethylamine is usually added to consume the HCl.
Synthesis of N-acetylpyrrolidine from pyrrolidine
When pyrrolidine react with acetyl chloride then there is a formation of N-acetylpyrrolidine as a final product.
In this reaction in the first step base is used to abstract the acidic proton from nitrogen atom and formation of negative charge on the nitrogen atom, In second step negative charge on the nitrogen atom attack the carbonyl carbon of acetyl chloride and there is formation of N-acetylpyrrolidine and hydrochloric acids as a by product.
Formation of N-acetylpyrrolidine
Over 30 million students worldwide already upgrade their learning with Vaia!
