Chapter 22: Q72P-a (page 1205)
Show how you would use the malonic ester synthesis to make the following compounds
Chapter 22: Q72P-a (page 1205)
Show how you would use the malonic ester synthesis to make the following compounds
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Get started for freeBiochemists studying the structure of collagen (a fibrous protein in connective tissue) found cross-links containing unsaturated aldehydes between protein chains. Show the structures of the side chains that react to form these crosslinks, and propose a mechanism for their formation in a weakly acidic solution.
Question:Show how you would use the Robinson annulation to synthesize the following compounds.
Predict the major products of the following reactions.
c)
The Knoevenagel condensation is a special case of the aldol condensation in which an active methylene compound reacts with an aldehyde or ketone, in the presence of a secondary amine as a basic catalyst, to produce a new C=C. Show the starting materials that made each of these by a Knoevenagel condensation.
For each molecule shown below,
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