Within each set of structures, indicate which will react fastest, and which slowest, toward nucleophilic addition in basic conditions.

(a)

(b)

(c)

Short Answer

Expert verified

(a) Second compound will react fastest toward nucleophilic addition reactions and first compound will react slowest toward nucleophilic addition reactions.

(b)Second compound will react fastest toward nucleophilic addition reactions and fourth compound will react slowest toward nucleophilic addition reactions.

(c) First compound will react fastest toward nucleophilic addition reactions and third compound will react slowest toward nucleophilic addition reactions.

Step by step solution

01

Nucleophilic addition

It involves the addition of a reagent across a multiple bond by the attack of a nucleophile at the electrophilic end of the multiple bond.

02

Explanation

(a)

Second compound (shown in red) will react fastest toward nucleophilic addition reactions since aldehydes are considered to be more electrophilic than the ketones. First compound (shown in blue) will react slowest toward nucleophilic addition reactions because it has a electron donor phenyl group at alpha position.

(b)

Second compound (shown in red) will react fastest toward nucleophilic addition reactions since aldehydes are considered to be more electrophilic than the ketones. Fourth compound (shown in blue) will react slowest toward nucleophilic addition reactions because it has a electron donor phenyl group at alpha position.

(c)

First compound (shown in red) will react fastest toward nucleophilic addition reactions since it has two electron withdrawing groups at the alpha position.Third compound (shown in blue) will react slowest toward nucleophilic addition reactions.

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