Log out Go to App
Go to App

Learning Materials

Features

Discover

Chapter 21: Q24P (page 1002)

What amino acid is formed when the aldehyde used in the Strecker synthesis is

a. acetaldehyde? b. 2-methylbutanal? c. 3-methylbutanal?

Short Answer

Expert verified

In Strecker synthesis, an aldehyde reacts with ammonia to form an imine. A nucleophilic addition reaction with cyanide ion forms an intermediate, which, when hydrolyzed, forms the amino acid.

Step by step solution

01

Strecker synthesis

In Strecker synthesis, an aldehyde reacts with ammonia to form an imine. A nucleophilic addition reaction with cyanide ion forms an intermediate, which, when hydrolyzed, forms the amino acid.

02

Formation of respective amino acids

a)

Treatment of acetaldehyde with HCN produces the corresponding α-aminonitrile which upon hydrolysis produces alanine. The reaction is as follows:

b)

Treatment of 2-methyl butanal with HCN produces the corresponding -amino nitrile which upon hydrolysis produces isoleucine. The reaction is as follows:

c)

Treatment of 3-methyl butanal with HCN produces the corresponding α-aminonitrile which upon hydrolysis produces leucine. The reaction is as follows:

Formation of leucine (c)

Unlock Step-by-Step Solutions & Ace Your Exams!

  • Full Textbook Solutions

    Get detailed explanations and key concepts

  • Unlimited Al creation

    Al flashcards, explanations, exams and more...

  • Ads-free access

    To over 500 millions flashcards

  • Money-back guarantee

    We refund you if you fail your exam.

Start your free trial

Over 30 million students worldwide already upgrade their learning with Vaia!

One App. One Place for Learning.

All the tools & learning materials you need for study success - in one app.

Get started for free

Most popular questions from this chapter

Draw the predominant form for glutamate in a solution with the following pH:

a.0 b. 3 c. 6 d. 11

a. What percentage of the α-amino group of lysine will be protonated at its pI?<25%50% >75%

b. Answer the same question for theε-amino group of lysine.

Identify the location and type of charge on the hexapeptide Lys-Ser-Asp-Cys-His-Tyr at each of the following pH values:

a. pH = 1 b. pH = 5 c. pH = 7 d. pH = 12

Reaction of a polypeptide with carboxypeptidase A releases Met. The polypeptide undergoes partial hydrolysis to give the following peptides.

What is the sequence of the polypeptide?

1. Ser, Lys, Trp4. Leu, Glu, Ser 7. Glu, His 10. Glu, His, Val

2. Gly, His, Ala 5. Met, Ala, Gly8. Leu, Lys, Trp11. Trp, Leu, Glu

3. Glu, Val, Ser 6. Ser, Lys, Val 9. Lys, Ser 12. Ala, Met

A mixture of amino acids that do not separate sufficiently when a single technique is used can often be separated by two-dimensional chromatography.In this technique, the mixture of amino acids is applied to a piece of filter paper and separated by chromatographic techniques. The paper is then rotated90°,and the amino acids are further separated by electrophoresis, producing a type of chromatogram called a fingerprint.Identify the spots in the fingerprint obtainedfrom a mixture of Ser, Glu, Leu, His, Met, and Thr.
See all solutions

Recommended explanations on Chemistry Textbooks

Ionic and Molecular Compounds

Read Explanation

Organic Chemistry

Read Explanation

Inorganic Chemistry

Read Explanation

Physical Chemistry

Read Explanation

The Earths Atmosphere

Read Explanation

Chemical Reactions

Read Explanation
View all explanations

What do you think about this solution?

We value your feedback to improve our textbook solutions.

Study anywhere. Anytime. Across all devices.

Sign-up for free