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Chapter 21: Q34P (page 1010)

Show the steps in the synthesis of the tetrapeptide Leu- Phe- Ala- Val

Short Answer

Expert verified

The answer is:

Step 1

Step 2

Step 3

Step by step solution

01

Step-by-Step Solution Step 1: Cysteine

There are a large number of amino acids in nature. Out of these, some are essential, and some are non-essential amino acids. Cysteine is an amino acid containing a sulfur atom.

02

Explanation

The steps in the synthesis of the tetrapeptide Leu- Phe- Ala- Val

Step 1


Step 2

Step 3

The obtained compound reacts with the trifluoroacetic acid and dichloromethane to give the final tetrapeptide.

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Most popular questions from this chapter

Explain the difference in the \({\bf{p}}{{\bf{K}}_{\bf{a}}}\) values of the carboxyl groups of alanine, serine, and cysteine.

Write the mechanism for the reaction of a cysteine side chain with iodoacetic acid.

What amino acid is formed using the N-phthalimidomalonic ester synthesis when the following alkyl halides are used in the third step?

(a)

(b)CH3SCH2CH2Br

Calculate the pI of each of the following amino acids:

a.asparagine b. arginine c. serine d. aspartate

A decapeptide undergoes partial hydrolysis to give peptides whose amino acid composition is shown. Reaction of the intact decapeptide with Edman’s reagent releases PTH-Gly. What is the sequence of the decapeptide?

1.Ala, Trp

2. Val,Pro,Asp

3. Pro, Val

4. Ala, Glu

5. Trp, Ala, Arg

6.Arg, Gly

7.Glu, Ala, Leu

8. Met, Pro, Leu, Glu
See all solutions

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