What is the configuration of the following compounds? (Use the given structures to answer the question.)

a. (-)-glyceric acid


b.(+)-isoserine


c. (+)-lactic acid

Short Answer

Expert verified
  1. R-configuration
  2. R-configuration
  3. R-configuration

Step by step solution

01

The R/S system of nomenclature.

Cahn, Ingold, and Prelog devised a mechanism that, no matter which way we look at the molecule, always yields the same name (unlike the wedge and dash notation).

As a result, this system is also known as the absolute Configuration or, more popularly, the R and S system.

02

Subpart (a) To determine the configuration of (-)-glyceric acid.

  • Because the group with thelowest priority is on the hatched wedge.
  • The arrow drawn from the COOH group to thegroup isclockwise.
  • (-)-glyceric acid has the R configuration.
03

Subpart (b) To determine the configuration of (+)-isoserine.

  • Because the group with the lowest priority is on the hatched wedge.
  • The arrow drawn from the COOH group to the group is clockwise.
  • (+)-isoserinehas the R configuration.
04

Subpart (c) To determine the configuration of (+)-lactic acid.

  • Because the group with the lowest priority is on the hatched wedge.
  • The arrow drawn from the COOH group to the group isclockwise.
  • (+)-lactic acidhas theR configuration.

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