Chapter 19: More About Amines • Reactions of Heterocyclic Compounds

Name the following:

a.

b.

c.

d.

e.

f.

Why is protonated pyrimidine $({\mathbf{pK}}_a\mathbf{=}\mathbf{1}\mathbf{.}\mathbf{0})$ more acidic than protonated pyridine$({\mathbf{pK}}_a\mathbf{=}\mathbf{5}\mathbf{.}\mathbf{2})$ ?

Question: Why is protonated pyrimidine ( pK_a = 1.0 ) more acidic than protonated pyridine ( pK_a = 5.2 ) ?

Name the following:

b.

c.

d.

Question: Name the following:

a.

b.

c.

d.

What are the products of the following reactions?

a.

b.

c.

d.

e.

f.

g.

h.

i.

Question: What are the products of the following reactions?

a.

b.

c.

d.

e.

f.

g.

h.

i.

Rank the following compounds from strongest acid to weakest acid:

Which of the following compounds is easier to decarboxylate?

or

Rank the following compounds from most reactive to least reactive in an electrophilic aromatic substitution reaction: