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Chapter 17: Q62P (page 848)

Show how the following compound can be synthesized from the given starting material.

Short Answer

Expert verified

The answer is,

Reaction mechanism

Step by step solution

01

Explanation

The reaction of acids on alcohol gives an alkene on undergoing dehydration reaction. And the reaction of ketone with strong bases like LDA, Lithium di-isopropyl amine to produce an enolate ion which undergoes reaction to give claisen condensation product.

02

Explanation

The reaction for the synthesis of the given compound is as shown below.

Reaction Mechanism

The reaction starts with the sulphuric acid reagent. The water molecule is eliminated from the compound giving an alkene.It is the treated with LDA in THF and 2-pentanone giving the product by condensation reaction.

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Most popular questions from this chapter

Describe three ways to synthesize the following compound:

What two carbonyl compounds are needed to synthesize each of the following compounds, using a Robinson annulation?

What alkyl bromide should be used in the acetoacetic ester synthesis of each of the following methyl ketones?

a. 2-pentanone b. 2-octanone c. 4-phenyl-2-butanone

Explain why the following carboxylic acids cannot be prepared by a malonic ester synthesis:

Question: Explain why the α-hydrogen of an N,N-disubstituted amide is less acidic (pKa= 30) than the α-hydrogen of an ester (pKa= 25).
See all solutions

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