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Chapter 24: Q3P (page 1106)

Show the mechanism for the reaction of glycerol with ATP to form glycerol-3-phosphate.

Short Answer

Expert verified

When glycerol reacts with adenosine triphosphate it produces glycerol-3-phosphate, adenosine diphosphate and a proton.

Step by step solution

01

Attack of ATP at the first phophorus

Glycerol, specifically,C3 , attacks at the first phosphorus atom which forms phosphate ion with the -CH2Ogroup by losing a proton. Thus glycerol-3-phosphate is formed.

02

Minor products formed

When glycerol-3-phosphate is formed, one phosphate ion in ATP is lost and forms ADP, i.e. adenosine diphosphate. So the products are glycerol-3-phosphate, ADP and a proton.

The complete mechanism is shown below:

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