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Chapter 24: Q44P (page 1126)

How many molecules of ATP are obtained from the complete (including the fourth stage of catabolism) metabolism of one molecule of a 16-carbon saturated fatty acyl-CoA?

Short Answer

Expert verified

108 molecules

Step by step solution

01

ATP formed by acetyl-CoA.

An acetyl-CoA formed 10 ATP molecules. So, eight molecules of acetyl-CoA will form 80 ATP molecules.

02

ATP formed by βoxidation

There are total 28 ATP molecules are formed 10.5 molecules by FADH2 and 17.5 molecules by NADH.

So, total ATP molecules are 108 molecules.

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Most popular questions from this chapter

Palmitic acid is a 16-carbon saturated fatty acid. How many molecules of acetyl-CoA are formed from one molecule of palmitic acid?

What would be the results of the experiment in Problem 53 if the radioactive AMP were added to the incubation mixture instead of radioactive pyrophosphate?

Why does the OH group add to the β-carbon rather than to the α-carbon in the second reaction in the β-oxidation of fats?

Which reactions in the citric acid cycle form a product with a new asymmetric center?

A student is trying to determine the mechanism for a reaction that uses ATP to activate a carboxylate ion, which reacts with a thiol. If the carboxylate ion attacks the gamma- phosphorous of ATP, the reaction products are the thioester, ADP, and phosphate. However, whether it attacks the alpha-phosphorous or the beta-phosphorous of ATP cannot be determined from the reaction products because the thioester, AMP, and pyrophosphate would be the products in both reactions. The mechanisms can be distinguished by a labelling experiment in which the enzyme, the carboxylate ion, ATP, and radioactively labelled pyrophosphate are incubated, and then the ATP is isolated. If the isolated ATP is radioactive, the attack occurs on the alpha-phosphorous. If it is not radioactive, an attack occurs on the beta- phosphorous. Explain these conclusions.
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