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Chapter 28: Q28-5P (page 950)
What RNA base sequence is complementary to the following DNA base sequence?
(5’) GGCTAATCCGT (3’)
The RNA base sequence which is complementary to the above DNA sequence can be written as .
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Question: Give an mRNA sequence that will code for the synthesis of mentenkephalin.
Tyr-Gly-Gly-Phe-Met
28-38 Valganciclovir, marketed as Valcyte, is an antiviral agent used for the treatment of cytomegalovirus. Called a prodrug, valganciclovir is inactive by itself but is rapidly converted in the intestine by hydrolysis of its ester bond to produce an active drug, called ganciclovir, along with an amino acid.
Show the structures of the products you would obtain hydroboration-oxidation of the following alkenes:
a)
b)
Draw the full structure of the RNA dinucleotide UA.
Propose structures for compounds that fit the following mass-spectral data:
(a) A hydrocarbon with\({{\bf{M}}^ + }{\rm{ = }}{\bf{132}}\)
(b) A hydrocarbon with\({{\bf{M}}^ + }{\rm{ = }}{\bf{1}}66\)
(c) A hydrocarbon with\({{\bf{M}}^ + }{\rm{ = 84}}\)
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