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Chapter 10: Q47E (page 308)

How might you use a Suzuki–Miyaura reaction to prepare the biarylcompounds below? In each case, show the two potential reactionpartners.

Short Answer

Expert verified

(a)

(b)

(c)

Step by step solution

01

Suzuki–Miyaura reaction

Suzuki miyaura reaction is an organic reaction, classified as a cross coupling reaction, where the coupling partners are boronic acid and an organohalide and the catalyst is a palladium complex.

02

Preparing Bi-aryl compounds by Suzuki miyaura reaction

The Suzuki- Miyaura reaction is Pd-catalyzed coupling reaction between an aromatic boronic acid and an aromatic vinyl halide. Two possible coupling reaction can yield the target product.

(a)

Preparation of Bi-aryl (a)

(b)

Preparation of Bi-aryl (b)

(c)

Preparation of Bi-aryl (c)

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