What product would you expect to obtain from reaction of with (R)-2-bromobutane? Show the stereochemistry of both the reactant and product.

The reaction is a nucleophilic substitution reaction where bond is broken and another is formed simultaneously. Two reacting species are involved in the rate determining step of the reaction. The term stands for substitution nucleophilic bimolecular.

${\mathrm{S}}_{\mathrm{N}}2$Reaction

Inversion of configuration is a process in which the configuration of an atom is changed. If the atom in question is a stereocenter, inversion of configuration usually changes R absolute configuration to S, and S into R. Inversion of configuration can also convert cis into trans, or trans into cis.

By identifying the leaving group and chirality center, draw the product carbon skeleton, inverting the configuration at the chirality center, and replace the leaving group (bromide) with the nucleophilic reactant (OH^-). Formation of product of the reactant with its Stereochemistry is shown below.

(R)-2-bromobutane (S)-2-butanol