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Chapter 29: Q29-15P (page 1008)

What α-keto acid is formed on transamination of leucine?

Short Answer

Expert verified

CH32CHCH2COCO2

Step by step solution

01

Draw the structure of leucine

The amino acid leucine has the following structure:

02

Apply the general scheme of transamination is degradation

Transamination is defined as the degradation of anα-AA by another α-AA.

  1. Deamination is used to remove the amino group as NH3.
  2. NH3 to urea conversion.
  3. The carbon skeleton of the remaining amino acid is transformed to anα-keto acid.
03

Applying this scheme to leucine

When this technique is used to leucine, it results in fragments such as

As a result, the α-keto acid produced is

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