How can you validate precision and accuracy?

Precision is validated by the repeatability of analyses of replicate samples and replicate portions of the same sample.

Accuracy:

Accuracy is validated by analyzing certified reference materials, by relating results from different analytical methods,

They are,

Fortification (spike) recovery,

Standard additions,

Calibration checks,

There are several ways to illustrate accuracy. Such actions include:

1. Performing calibration checks in order to assure that the instruments are properly calibrated and therefore would work properly;

2. Testing for fortification/spike recoveries - in this process, we can see if the response from a calibration curve matches the response to the spike;

3. Introducing quality control samples for the elimination of any bias introduced; and

4. Introducing blanks to account for the interference of other species in the sample. To demonstrate precision, we can replicate both our samples, and portions of the same sample.