List the three different cases that we studied for comparison of means, and write the equations used in each case.

Short Answer

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Case 1: Comparing a Measured Result with an Accepted Result that is known

tcalc=x¯-μns

Case 2: Comparing Two Samples/Methods Means isspooled=s12n1-1+s22n2-1n1+n2-nt

Case 3: Individual differences are compared using a paired t test; standard deviation of differences is a necessary computationsd=di-d¯2n-2

Step by step solution

01

Definition of mean and standard deviation of difference

  • Average value derived by summing all values and dividing by the total number of values (science: statistics).
  • The standard deviation (SD) is a measure of the variability, or dispersion, between individual data values and the mean.
  • Whereas the standard error of the mean (SEM) is a measure of how far the sample mean (average) of the data is expected to differ from the genuine population mean. Always, the SEM is smaller than the SD.
02

Determine a measured result with an accepted result and compare two samples means

Case 1: Comparing a Measured Result with an Accepted Result that is known

tcalc=x¯-μns

The confidence interval (CI) formula is used to derive the expression above.

Case 2: Comparing Two Samples/Methods Means

tcalc=x¯1-x¯2spooledn1n2n1+n2

Calculate the prerequisites:

spooled=s12n1-1+s22n2-1n1+n2-nt

03

Determine the individual difference and comparing by using the paired t- test

Case 3: Individual differences are compared using a paired t test.

tcalc=d8dn

Standard deviation of differences is a necessary computation

sd=di-d¯2n-2

Where: d3=difference of each sample andd¯= mean of differences

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Most popular questions from this chapter

Sample 8 of Problem 4-3 was analyzed seven times, with x¯=1.52793and s=0.00007. Find the 99 % confidence interval for sample 8 .

Now we use a built-in routine in Excel for the paired t test to see if the two methods in Problem 4-15 produce significantly different results. Enter the data for Methods 1 and 2 into two columns of a spreadsheet. For Excel 2007 and 2010, find Data Analysis in the Data ribbon. If Data Analysis does not appear, follow the instructions at the beginning of Section 4-5 to load this software. Select Data Analysis and then select t-Test: Paired Two Sample for Means. Follow the instructions of Section 4-5 and the routine will print out information including tculculaed (labeled "tStat")andtuable(labeled " t Critical two-tail"). You should reproduce the results of Problem 4-15.

Traces of toxic, man-made hexachlorohexanes in North Sea sediments were extracted by a known process and by two new procedures, and measured by chromatography.

(a) Is the concentration parts per million, parts per billion, or something else?

(b) Is the standard deviation for procedure B significantly different from that of the conventional procedure?

(c) Is the mean concentration found by procedure B significantly different from that of the conventional procedure?

(d) Answer the same two questions as parts (b) and (c) to compare procedure A to the conventional procedure.

If you measure a quantity four times and the standard deviation is 1.0% of the average, can you be 90% confident that the true value is within 1.2% of the measured average?

Logarithmic calibration curve. Calibration data spanning five orders of magnitude for an electrochemical determination of p-nitrophenol are given in the table. (The blank has already been subtracted from the measured current.) If you try to plot these dataon a linear graph extending from 0 to 310μg/mLand from 0 to 5260nA, most of the points will be bunched up near the origin. To handle data with such a large range, a logarithmic plot is helpful.

Overwhatrangeisthelog-logcalibrationlinear?

(a) Make a graph of log (current) versus log( concentration). Over what range is the log-log calibration linear?

(b)FindtheequationoftheLine

InTheform log(current)=m×log(concentration)+b

(c) Find the concentration of p-nitrophenol corresponding to a signal of 99.9nA.

(d) Propagation of uncertainty with logarithm. For a signal of 99.9nA, log (concentration) and its standard uncertainty turn out to be 0.68315±0.04522. With rules for propagation of uncertainty from Chapter 3, find the uncertainty in concentration.

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