Many prescribed drugs must reach a “maintenance level” in the bloodstream to be effective. Say a person takes 300 milligrams of wonder drug Excellente´ per day and that whatever level of Excellente´ is in the bloodstream, p% is eliminated in one 24-hour period.

Find the approximate level of drugs during the first week.

Short Answer

Expert verified

L2=140L3=356L5=479.96L6=490.784L7=496.31L4=442.40

Step by step solution

01

Step 1. Given

The amount of drug in milligrams a person takes D=300 mg.

The percentage p of the drug eliminated from the blood stream after 24 hours = 60

02

Step 2. Dose on Second day

ThedailydoseofthemedicineisD.LetL1istheamountofdruginthebloodstreamatthestart.Hence,L1=DAfter24hours50%ofthedrughasbeeneliminatedfromthebloodstreamandtheseconddoseistaken.Hence,L2=(1-p100)L1+D......(1)Ingeneral,afterkdays.Lk+1=(1-p100)Lk+D.....Substitutingk=1in(2)Therefore,L2=(1-60100)(300)+300Simplify,L2=(1-0.60)(300)+300L2=(0.40)(300)+300=40+100L2=140

03

Step 3. Dose on Third day

L3=(1-p100)L1+D......(1)Ingeneral,afterkdays.Lk+1=(1-p100)Lk+D.....Substitutingk=2in(2)Therefore,L2=140Simplify,L3=(1-0.60)(140)+300L3=(0.40)(140)+300L3=356

04

Step 4. Dose on fourth day

L4=(1-p100)L3+D......(1)Ingeneral,afterkdays.Lk+1=(1-p100)Lk+D.....Substitutingk=3in(2)Therefore,L3=356Simplify,L4=(1-0.60)(356)+300L4=(0.40)(356)+300L4=442.40

05

Step 5. Dose on fifth day

L5=(1-p100)L4+D......(1)Ingeneral,afterkdays.Lk+1=(1-p100)Lk+D.....Substitutingk=4in(2)Therefore,L4=442.40Simplify,L5=(1-0.60)(442.40)+300L5=(0.40)(442.40)+300L5=479.96

06

Step 6. Dose on sixth day

L6=(1-p100)L5+D......(1)Ingeneral,afterkdays.Lk+1=(1-p100)Lk+D.....Substitutingk=5in(2)Therefore,L5=476.96Simplify,L6=(1-0.60)(476.96)+300L6=(0.40)(476.96)+300L6=490.784

07

Step 7. Dose on seventh day

L7=(1-p100)L6+D......(1)Ingeneral,afterkdays.Lk+1=(1-p100)Lk+D.....Substitutingk=5in(2)Therefore,L6=490.78Simplify,L7=(1-0.60)(490.78)+300L7=(0.40)(490.78)+300L7=496.31

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