Aspirin prevents blood from clotting and so helps prevent strokes. The Second European Stroke Prevention Study asked whether adding another anticlotting drug named dipyridamole would be more effective for patients who had already had a stroke. Here are the data on strokes during the two years of the study:

(a) Summarize these data in a two-way table.

(b) Make a graph to compare the rates of strokes for the four treatments. Describe what you see.

(c) Explain in words what the null hypothesis H0: p1 = p2 = p3 = p4 says about the incidence of strokes.

(d) Find the expected counts if H0 is true, and display them in a two-way table similar to the table of observed counts

Short Answer

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a.

b.

(c) The null hypothesis states that the proportion of successes for each treatment is the same, based on the participants' smoking behaviours.

(d) The expected counts are the total of the rows multiplied by the total of the columns, divided by the sample size

Step by step solution

01

Part (a)Step 1: Given information

Given in the question that, Aspirin prevents blood from clotting and so helps prevent strokes. The Second European Stroke Prevention Study asked whether adding another anticlotting drug named dipyridamole would be more effective for patients who had already had a stroke. Here are the data on strokes during the two years of the study:

We need to summarize these data in a two-way table .

02

Part(a) Step 2: Explanation

Aspirin reduces blood coagulation and hence helps to avoid strokes, according to the question. As a result, the question includes statistics on strokes during the two-year research. Thus, in a two-way table, the number of no strokes equals the number of patients minus the number of strokes, that is,


StrokeNo stroke
Placebo250
1399
1649
Aspirin206
1443
1649
Dipyridamole211
1443
1654
Both157
1493
1650

824
5778
6602
03

Part(b) Step 1: Given information

Given in the question that, a table which contains data on strokes during the two years of the study:

We need to make a graph to compare the rates of strokes for the four treatments.

04

Part (b) Step 2: Explanation

Aspirin reduces blood coagulation and hence helps to avoid strokes, according to the question. As a result, the question includes statistics on strokes during the two-year research. Thus, in a two-way table, the number of no strokes equals the number of patients minus the number of strokes, that is,

As a result, the proportion in each category is computed by dividing the number of strokes/no strokes by the row total given in the last column:


StrokeNo Stroke
Placebo0.1516
0.8484
Aspirin0.1249
0.8751
Dypyridamole0.1276
0.8724
Both0.0952
0.9048

As a result, the following graph can be used to compare the success rates of the four treatments:

Thus, by looking at the histogram we note that the proportions of strokes/no strokes do not seems to vary much by group.

05

Part(c) Step 1: Given information

Given in the question that, Aspirin prevents blood from clotting and so helps prevent strokes. The Second European Stroke Prevention Study asked whether adding another anticlotting drug named dipyridamole would be more effective for patients who had already had a stroke. Here are the data on strokes during the two years of the study:

We need to explain in words what the null hypothesis H0:p1=p2=p3=p4says about the incidence of strokes.

06

Part(c) Step 2: Explanation

Aspirin reduces blood coagulation and hence helps to avoid strokes, according to the question. As a result, the question includes statistics on strokes during the two-year research. Thus, in a two-way table, the number of no strokes equals the number of patients minus the number of strokes, that is,

As a result, the null hypothesis in the question is written as follows:

H0:p1=p2=p3=p4

And the null hypothesis states that the proportion of successes for each treatment is the same, based on the participants' smoking behaviours.

07

Part(d) Step 1: Given information

Given in the question that, Aspirin prevents blood from clotting and so helps prevent strokes. The Second European Stroke Prevention Study asked whether adding another anticlotting drug named dipyridamole would be more effective for patients who had already had a stroke. Here are the data on strokes during the two years of the study:

We need to find the expected counts if H0is true, and

display them in a two-way table similar to the table of observed counts

08

Part (d) Step 2: Explanation

Aspirin reduces blood coagulation and hence helps to avoid strokes, according to the question. As a result, the question includes statistics on strokes during the two-year research. Thus, in a two-way table, the number of no strokes equals the number of patients minus the number of strokes, that is,

As a result, the null hypothesis in the question is written as:

H0:p1=p2=p3=p4

As a result, the expected counts are the total of the rows multiplied by the total of the columns, divided by the sample size n=6602, as follows:

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