The potential difference across a cell membrane from outside to inside is initially at \(-90 \mathrm{mV}\) (when in its resting phase). When a stimulus is applied, Na" ions are allowed to move into the cell such that the potential changes to \(+20 \mathrm{mV}\) for a short amount of time. (a) If the membrane capacitance per unit area is $1 \mu \mathrm{F} / \mathrm{cm}^{2},\( how much charge moves through a membrane of area \)0.05 \mathrm{cm}^{2} ?\( (b) The charge on \)\mathrm{Na}^{+}\( is \)+e$ How many ions move through the membrane?

Short Answer

Expert verified
How many sodium ions (Na+) move through the membrane, given that the charge on Na+ is +e? Answer: The amount of charge that moves through the membrane is 5.5 x 10^-9 C. Approximately 3.4 x 10^10 sodium ions move through the membrane.

Step by step solution

01

Calculate the change in potential difference

First, calculate the change in potential difference (voltage) by finding the difference between the final voltage (+20 mV) and the initial voltage (-90 mV): ΔV = V_final - V_initial ΔV = (20 - (-90)) mV ΔV = 110 mV
02

Convert potential difference to volts

Since we need to work in standard units (SI units), we need to convert the potential difference from millivolts (mV) to volts (V): ΔV = 110 mV * (1 V / 1000 mV) = 0.110 V
03

Calculate the charge moved through the membrane

Now, we can use the capacitance formula to find the charge (Q) that moves through the membrane: Q = C * ΔV Given the membrane capacitance per unit area (C/A) is 1 μF/cm² and the area (A) is 0.05 cm², we can find the total capacitance (C) as follows: C = (C/A) * A C = (1 μF/cm²) * (0.05 cm²) C = 0.05 μF Now, convert the capacitance to standard units (farads) by multiplying by 1x10⁻⁶ C = 0.05 μF * (1 F / 10⁶ μF) = 5 x 10^-8 F Finally, calculate the charge (Q): Q = C * ΔV Q = (5 x 10^-8 F) * (0.110 V) Q = 5.5 x 10^-9 C Thus, the charge that moves through the membrane is 5.5 x 10^-9 C.
04

Calculate the number of sodium ions

Now that we have found the charge that moves through the membrane, we can find the number of sodium ions (N) by dividing the total charge (Q) by the charge of a single Na+ ion (+e = 1.6 x 10^-19 C): N = Q / e N = (5.5 x 10^-9 C) / (1.6 x 10^-19 C/ion) N ≈ 3.4 x 10^10 ions Thus, approximately 3.4 x 10^10 sodium ions move through the membrane.

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